Irritable Bowel Syndrome with
Constipation
Addressing irritable bowel syndrome with constipation
Irritable bowel syndrome with constipation (IBS-C) is a gastrointestinal disorder characterized by recurring abdominal discomfort or pain, bloating, and infrequent bowel movements or difficulty passing stools. It falls under the broader category of irritable bowel syndrome (IBS), which is a disorder of the gut-brain interaction affecting the large intestine. IBS-C is associated with significantly impaired quality of life, reduced productivity, and substantial economic burden.
The causes of IBS-C and the severity of the symptoms are different in each patient, with management focused on relieving symptoms and improving overall quality of life through dietary modifications, lifestyle changes, stress management techniques, and pharmacological interventions. As each patient has unique needs, there is no one-size-fits-all treatment approach and there is a need for different medications with different mechanisms of action.
Facts and figures
10-15%
IBS is common and affects about 10-15% of the population in the U.S.
2/3
About 2 in 3 IBS sufferers are female.
<50
Most people with IBS are under the age of 50. However, many older adults suffer as well.
90%
of IBS-C patients surveyed as part of the IBS in America supplemental survey reported “some” or “significant” negative impact of IBS-C on their life.
39%
of IBS-C patients in the IBS in America supplemental survey described their quality of life as “poor” or “fair".
11 Days
IBS-C patients in the IBS in America 2024 supplemental survey reported that their mental health had been “not good” for an average of 11 out of the previous 30 days.
Patient Advocacy Partners
We proud to partner with organizations that raise awareness for those living with IBS-C and support the patient journey.
Resources
IBS-C can have a tremendous impact on patients, their families and caregivers. These resources can provide you with additional information and access to research and support.
Ardelyx created ArdelyxAssist™ an innovative, digital-forward, high-touch patient services program. ArdelyxAssist provides a broad range of access and affordability support for patients, with integration into medical office work processes and connectivity to patients and healthcare providers.